Prenatal diagnosis in rare bleeding disorders-An unresolved issue?
نویسندگان
چکیده
منابع مشابه
Rare bleeding disorders: diagnosis and treatment.
Despite the worldwide prevalence of rare bleeding disorders (RBDs), knowledge of these conditions and their management is suboptimal; health care professionals often have little diagnostic and treatment experience with variable access to diagnostic modalities required for accurate identification. Therefore, patients often experience morbidity and mortality due to delayed diagnosis. As RBDs repr...
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A large body of evidence suggests that aldosterone excess is a common cause of hypertension with a prevalence of primary aldosteronism (PA) of 10% in patients with mildto-moderate hypertension and 20% in patients with resistant hypertension.1 Experimental and clinical data also demonstrate that aldosterone excess contributes importantly to the development and progression of cardiorenal disease....
متن کاملRare bleeding disorders.
During the haemostatic response, the formation of a primary platelet plug limits bleeding and provides a surface for clotting factors to assemble and become activated. The initial platelet plug is stabilized by fibrin monomers, covalently cross-linked by FXIII, forming a platelets-fibrin thrombus. Defects in platelets as well as inherited deficiencies of coagulation factors including fibrinogen...
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Premature birth is the world's leading cause of neonatal mortality with worldwide estimates indicating 11.1% of all live births were preterm in 2010. Preterm birth rates are increasing in most countries with continual differences in survival rates amongst rich and poor countries. Preterm birth is currently an important unresolved global issue with research efforts focusing on uterine quiescence...
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TRPA1 was originally characterized as a cold-activated ion channel; however, since the initial description there has been some disagreement about its role in cold sensation. Here, we review the literature on the function of TRPA1 as a cold sensor. Many studies have demonstrated that TRPA1 can be activated by cold when expressed in heterologous systems, but its role as a cold sensor in native pe...
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ژورنال
عنوان ژورنال: International Journal of Laboratory Hematology
سال: 2018
ISSN: 1751-5521
DOI: 10.1111/ijlh.12789